CLONALITY ANALYSIS AND IDH1 AND IDH2 MUTATION DETECTION IN BOTH COMPONENTS OF DEDIFFERENTIATED CHONDROSARCOMA, IMPLICATED ITS MONOCLONAL ORIGIN

Clonality analysis and IDH1 and IDH2 mutation detection in both components of dedifferentiated chondrosarcoma, implicated its monoclonal origin

Dedifferentiated chondrosarcoma (DDCS) is a highly malignant tumor that belongs to an uncommon subtype of chondrosarcoma with a poor prognosis.Microscopically, it is composed of highly differentiated chondrosarcoma and highly malignant noncartilaginous sarcomas with an abrupt interface.The question of whether the two components originated from the

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NOD/scid IL-2Rgnull mice: a preclinical model system to evaluate human dendritic cell-based vaccine strategies in vivo

Abstract Background To date very few systems have been described for preclinical investigations of human cellular therapeutics in vivo.However, the ability to carry out comparisons of new cellular vaccines in vivo would be of substantial interest for design of clinical studies.Here we describe a humanized mouse model to assess the efficacy of vario

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Two Roles for the Tenebrio molitor Relish in the Regulation of Antimicrobial Peptides and Autophagy-Related Genes in Response to Listeria monocytogenes

Relish is a key NF-κB transcription factor of the immune-deficiency (Imd) pathway that combats infection by regulating antimicrobial peptides (AMPs).Understanding of the fundamental role of delta gamma blanket Tenebrio molitor Relish (TmRelish) in controlling of Listeria monocytogenes virulence through the regulation of both AMPs and autophagy

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PENEGAKAN HUKUM TINDAK PIDANA KORUPSI OLEH KEJAKSAAN

Abstract Corruption needs to be prevented and tackled not only because of its foul, but also economically cause financial losses to the state and is a violation of the rights of the social and economic community.The results showed that the number of corruption is still increase caused by factors such as lack of understanding of the law enforcement

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Implementation Of The Second Re-Vote In Labuhan Batu In 2020

In light of the Re-Voting (PSU) process during the 2020 concurrent elections, this research sought to critically evaluate the performance of the KPPS Labuhanbatu Regency.Utilizing a qualitative case study methodology, a comprehensive dataset was compiled from in-depth interviews kel instruments soil tester and meticulous document analysis, offering

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